Rice bran
Plant-based source containing naturally occurring polysaccharides.
BIOBRAN® MGN-3 ARABINOXYLAN
BioBran® MGN-3 is an arabinoxylan complex derived from rice bran and produced through a special enzymatic process using enzymes from shiitake mycelium.


MGN-3 ARABINOXYLAN
BioBran® MGN-3 is a food supplement based on modified rice bran. The raw material contains complex polysaccharides. Enzymatic processing produces smaller, water-soluble arabinoxylan structures. The reference book behind this page describes the product’s development since the early 1990s and summarises laboratory, animal and small human studies.
Plant-based source containing naturally occurring polysaccharides.
Processing with enzymes from Lentinula edodes mycelium.
A standardised MGN-3 complex.
SCIENTIFIC BACKGROUND
The research summarised in the book focuses on markers of innate immunity, especially natural killer (NK) cells, macrophages and cytokine signalling. The evidence comes from different study designs and should not be treated as equally strong.
Laboratory and small human studies examined changes in NK-cell activity after MGN-3.
In-vitro research explored phagocytosis and macrophage activation.
Other studies looked at signalling molecules such as interferons, TNF and interleukins.
Study of human natural killer-cell activity and modified rice-bran arabinoxylan.
International Journal of Immunotherapy 2, 89–99In-vitro research on TNF-α and interferon signalling in peripheral blood lymphocytes.
Cancer Detection and Prevention 24(4)In-vitro study of macrophage phagocytosis with MGN-3/BioBran.
International Journal of Immunopathology and Pharmacology 17(3), 283–292Animal study of NK-cell activity in aged mice.
Journal of Pharmacy and Pharmacology 56(12), 1581–1588Study in older adults concerning immunomodulation and common-cold frequency.
BioFactors 21, 185–187FURTHER INFORMATION
BioBran MGN-3 is listed on the official Pfeifer Protocol website among the food supplements described there. The external page provides additional background information about BioBran and the integrative treatment approach.
BUY BIOBRAN MGN-3
Two formats with clearly stated amounts of Arabinoxylan MGN-3.

50 tablets containing 250 mg Arabinoxylan MGN-3 each. A convenient daily format.
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30 sachets containing 1000 mg Arabinoxylan MGN-3 each, for dissolving in water.
Visit medpro shopFAQ
Arabinoxylans are plant polysaccharides found in cereal cell walls. In BioBran they are derived from rice bran.
Rice bran is partially hydrolysed with enzymes from shiitake mycelium, producing smaller, water-soluble components of the MGN-3 complex.
Research mainly addresses immune laboratory markers such as NK-cell activity, macrophages and cytokines. Some studies are in vitro or animal studies, while several human studies are small or older.
No. BioBran is a food supplement. Seek medical advice in case of illness, pregnancy, breastfeeding or regular medication.
Tablets contain 250 mg each; sachets contain 1000 mg each. Follow the label, recommended use and any advice from your healthcare professional.
Food supplements should not be used as a substitute for a balanced, varied diet and a healthy lifestyle. Do not exceed the recommended daily intake. Keep out of reach of children.
MEDPRO SHOP
Product details, directions for use and ordering are available in the medpro shop.